Your Resource Center for Osteoporosis Education

Help your patients strengthen their bones

Fragility fractures are strong predictors for future fracture risk.1,2

Also known as low-trauma fractures, fragility fractures may indicate the presence of osteoporosis in postmenopausal women.2,3


For postmenopausal women, osteoporosis-related fractures can mean more than a broken bone.

A fragility fracture can potentially affect a patient's daily life, result in pain at the fracture site, or complications from hospitalizations.4-6

the-perspective-of-the-patient-with-osteoporosis
Another point of view: The perspective of the patient with osteoporosis

Osteoporosis is a chronic disease that can impact a patient's life.6 Learn about communication strategies that help patients understand their diagnosis and treatment options.

#usa-785-80091
fragility-fractures-warning-signs-for-osteoporosis
Fragility fractures: Warning signs for osteoporosis

Understand why fragility fractures are warning signs for osteoporosis and subsequent fracture risk, and learn about the possible clinical, personal, and economic burden associated with fragility fractures.1,2,6,7

#usa-785-80027
the-science-of-bone-remodeling
The science of bone remodeling

Improve your understanding of osteoporosis with this in-depth look at the science of bone remodeling.

#usa-785-81333
role-of-sclerostin-in-postmenopausal-osteoporosis
Role of sclerostin in postmenopausal osteoporosis

The basic science behind a fragility fracture is revealed here, with a specific focus on understanding the cellular mechanisms influencing bone formation. Sclerostin, a negative regulator of bone formation that inhibits WNT signaling, is introduced.

#usa-785-81330
the-role-of-the-rank
Advancing the understanding of postmenopausal osteoporosis: The role of the RANK ligand pathway in osteoclast-mediated bone loss

The RANK ligand pathway plays a key role in postmenopausal bone loss and osteoporosis. Watch the video to learn how declining estrogen levels following menopause affect RANK ligand expression and osteoclast-mediated bone resorption.

#usa-785-81347
bone-remodeling-and-modeling
Bone remodeling and modeling

Discover how the skeleton changes across the human lifespan. Learn about the dynamic process of bone remodeling and understand factors that lead to changes in bone mass.

#usa-785-81334
osteoporosis-screening-diagnosis-and-treatment-of-high-risk-patients
Osteoporosis screening, diagnosis, and treatment of high-risk patients

Screening for osteoporosis is the first step in mitigating fracture risk.2,6,7 In this video, learn what key questions to ask to identify patients at risk for osteoporosis and fractures, what tools can be used for risk assessment, and what patients are at high risk for fracture and eligible for treatment.

#usa-785-80042
what-have-we-learned-from-modeling-bone-decay
What have we learned from modeling bone decay?

This unique perspective uses real data and cutting-edge algorithms to demonstrate progressive bone loss associated with aging. The accelerated loss of trabecular and cortical bone after menopause is a key contributor to future fracture risk, which can be avoided with appropriate diagnosis and timely treatment.6,8

#usa-785-80106
the-perspective-of-the-patient-with-osteoporosis
Another point of view: The perspective of the patient with osteoporosis

Osteoporosis is a chronic disease that can impact a patient's life.6 Learn about communication strategies that help patients understand their diagnosis and treatment options.

#usa-785-80091

Globally, 1 in 3 women over the age of 50 will experience fragility fractures.4

By evaluating postmenopausal patients and educating them on osteoporosis management options, healthcare professionals may help reduce the risk of fragility fractures.2,4

Discover the science of osteoporosis
Submit a medical inquiry or find an Amgen Medical Science Liaison in your area to connect with

1. Kanis JA, et al. Bone. 2004;35:375-382. 2. Camacho PM, et al. Endocr Pract. 2020;26(suppl 1):1-46. 3. Office of the Surgeon General. https://www.ncbi.nlm.nih.gov/books/NBK45525/. Accessed January 18, 2021. 4. International Osteoporosis Foundation. https://www.osteoporosis.foundation/facts-statistics/epidemiology-of-osteoporosis-and-fragility-fractures. Accessed January 18, 2021. 5. Inacio MCS, et al. Perm J. 2015;19:29-36. 6. National Osteoporosis Foundation. Clinician’s Guide to Prevention and Treatment of Osteoporosis. Washington, DC: National Osteoporosis Foundation; 2014. 7. U.S. Department of Health and Human Services. Bone Health and Osteoporosis: A Report of the Surgeon General. Rockville, MD: US Dept of Health and Human Services, Office of Surgeon General, 2004.

These materials are provided for educational and non-commercial purposes only. All materials provided herein are licensed for use only under the Creative Common Attribution-Non-Commercial-No Derivatives 4.0 International Public License linked here.